OUR TEAM

Lawrence B. Daniels, M.D.

Neurosurgeon

Pediatric and Adult Neurosurgery

Dr. Daniels is a fellowship trained pediatric neurosurgeon who is comfortable with the entire scope adult and pediatric neurosurgery. After graduating from UCLA’s School of Medicine, Dr. Daniels was awarded the Washington Scholars Research Fellowship at the Maxine Dunitz Neurosurgical Institute. During this research fellowship Dr. Daniels worked on the development of a dendritic cell vaccine for malignant brain tumors. Dr. Daniels also worked on research that aimed to selectively increase the permeability of the blood-brain-tumor barrier in an attempt to increase the amount of chemotherapy that enters cancers that travel to the brain from other parts of the body. Dr. Daniels completed his neurosurgical residency training at the Albert Einstein College of Medicine and pediatric neurosurgical fellowship training at the Children’s Hospital of Philadelphia. Dr. Daniels has research interests in neuro-oncology and craniofacial surgery and is currently conducting clinical and translational studies in both areas.

Curriculum Vitae

Education/Training/Employment

Feb 10, 2015 – Present
New Neurons Neurosurgical Institute, Chatham, NJ
Director

Sept 1, 2013 – Feb 10, 2015
Advanced Neurosurgeons Associates, Rutherford, NJ
Attending Physician

July 02, 2012 – June 30, 2013
Children’s Hospital of Philadelphia, Philadelphia, PA
Pediatric Neurosurgery Fellowship

Aug 01, 2006 – June 30, 2012
Albert Einstein College of Medicine, Bronx, NY
Neurosurgery Residency

July 01, 2006 – July 31, 2006
Albert Einstein College of Medicine, Bronx, NY
Pediatric Surgery Rotation

July 1, 2005 – June 30, 2006
University of California, San Francisco East Bay Program, Oakland, CA
General Surgery Internship

July 1, 2004 – June 30, 2005
Cedar Sinai Medical Center, Maxine Dunitz Neurosurgical Institute, Los Angeles, CA
Research Fellowship

June 01, 2000 – June 04, 2004
University of California, Los Angeles, Los Angeles, CA
Medical Degree

University of Southern California, Los Angeles, CA

June 01, 1996 – June 30, 2000
Bachelor of Science, Business Administration
June 01, 1996 – June 30, 2000
Bachelor of Science, Psychology

Awards

2004-2005
Washington Scholars Fellowship

2002-2003
National Medical Fellowship

1997-2000
USC General Scholarship

1998-1999
Mersereau Scholarship

1997-1998
USC Ebonics Scholarship

Aug 1997
USC Psychology Honors’ Program

Jan 1997
USC Business School Marshall Honors’ Program

Membership

2014 – present
Mentors in Medicine
Board of Directors

2014 – present
International Society of Pediatric Neurosurgery
Active Member

Lectures/Publication/Presentations

Use of External Distraction Devices and ICP Monitor for Gradual Cranial Vault Expansion as a Treatment for Primary Craniocerebral Disproportion: A Series of Two Identical Twins. Daniels, L; Sandler, A; Ciminello, F; Fried, A. Childs Nerv Syst. 2014 Nov; 30(11):1913-1995

42th Annual Meeting of the International Society for Pediatric Neurosurgery, Rio de Janeiro, Brazil, November 9-13th, 2014 (Presentation)
“Use of External Distraction Devices and ICP Monitor for Gradual Cranial Vault Expansion as a Treatment for Primary Craniocerebral Disproportion: A Series of Two Identical Twins.” A case series advocating a novel therapeutic approach for treating patients with craniocerebral disproportion.

Comparative effectiveness of treatment options for pediatric craniopharyngiomas. Ali, ZS;Bailey, RL; Daniels, LB; Vakhshort, V; Lewis DJ; Hossain, AT; Sitterley, KY; Lee, JY; Storm, PB; Heuer GC; Stein, SC. J Neurosurg Pediatrc, 2014 vol 13(2) pp. 178-88.

One-Year Experience In Efforts to Establish and Bank Tumor Cell Lines For Every Patient that Undergoes a Tumor Resection. Lawrence B. Daniels M.D., Amy Park, James T. Goodrich, M.D., Rick Abbott M.D., Richard Gorlick M.D., Karen Weidenheim M.D. Child’s Nervous System September 2012, Volume 28, Issue 9, pp 1589-1669

Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol. Sandler AL1, Goodrich JT, Daniels LB 3rd, Biswas A, Abbott R. Childs Nerv Syst. 2013 Nov;29(11):1997-2010.

Successful treatment of post-shunt craniocerebral disproportion by coupling gradual external cranial vault distraction with continuous intracranial pressure monitoring. Sandler AL1, Daniels LB 3rd, Staffenberg DA, Kolatch E, Goodrich JT, Abbott R. J Neurosurg Pediatr. 2013 Jun;11(6):653-7.

Infections of the Spinal Subdural Space in Children: A Series of Eleven Contemporary Cases and Review of All Published Reports. A Multi-National Collaborative Effort. Adam L. Sandler MD, Dominic Thompson MBBS, BSc, FRCS, James T. Goodrich MD ,PhD, Jasper van Aalst MD Eliezer Kolatch, BA, Mostafa El Khashab, MD, PhD, Farideh Nejat MD, , Erwin Cornips MD, Sandeep Mohindra MS, MCh, FRCS Ed, Rahul Gupta MCh, Reza Yassari MD MS, Lawrence B. Daniels III, MD, Arundhati Biswas, MD and Rick Abbott1 MD. Childs Nervous System, 2013 Jan;29(1):105-17.

Marvelous medicine: the untold story of the Wade-Dahl-Till valve. Adam L. Sandler, MD, Donald Sturrock, Jane Branfield ,BSc, MA, DipArch, I. Rick Abbott MD, James T. Goodrich MD, PhD, Arundhati Biswas, MD, Lawrence B. Daniels III, MD and Eugene S. Flamm MD. J Neurosurg Pediatr. 2012 May;9(5):482-90.

Cranial Vault Expansion as Treatment for Recalcitrant Debilitating Headaches in ShuntDependant Patients with Functioning Shunts: A Series of three patients. Daniels L, Sandler A, Biswas A, Staffenberg D, Abbott I. Child’s Nervous System Vol 27, Number 10 (2011), 1751-1850

39th Annual Meeting of the International Society for Pediatric Neurosurgery, Goa, India, October 16 -20, 2011 (Presentation)
“Cranial Vault Expansion as Treatment for Recalcitrant Debilitating Headaches in ShuntDependant Patients with Functioning Shunts: A Series of three patients.” A case series outlining a diagnostic and therapeutic protocol for evaluating patients with craniocerebral disproportion that would benefit from cranial vault expansion procedures.

Familial glioblastoma multiforme in two non-nuclear family members: A case report. Daniels L, Shaya M, Nordberg M, Shorter C, Fowler M, Nanda A. Journal of the Louisiana State Medical Society. 2007 Jul-Aug;159(4):215-22.

Feb 2002
Western Medical Research Forum, Abstract Publication and Presentation
“Analysis of spontaneously occurring programmed cell death in adult rats.” The objective of this study analyzed programmed cell death in various regions of the adult rat brain.

Aug 2002
UCLA School of Medicine, Poster Presentation
“Analysis of spontaneously occurring programmed cell death in adult rats.” The objective of this study analyzed programmed cell death in various regions of the adult rat brain.

Feb 2002
Western Medical Research Forum, Abstract Publication
“Analysis of spontaneously occurring programmed cell death in adult rats.” The objective of this study analyzed programmed cell death in various regions of the adult rat brain

Research Experience

Aug 2010- July 2012
Prospective and Retrospective Clinical Study (Lead Investigator)
“Analysis of molecular markers that may discriminate different survival subsets in pediatric patients with tumors of the nervous system.”
The aim of this study is to identify molecular and genetic markers that can be used to better stratify pediatric patients with common nervous system neoplasms based on risk, response to therapy and clinical outcome. This study is IRB approved with active patient enrollment

Oct 2010- July 2012
Prospective Clinical Study (Lead Investigator)
“A Children’s Hospital at Montefiore Protocol for Collecting and Banking and rapidly creating cell lines from Pediatric Brain Tumors.”
In this study we plan to enhance the Pediatric Brain Tumor Bank at the Children’s Hospital at Montefiore by banking optimally preserved tumor specimen and establishing a protocol to rapidly create and store individual tumor cell lines for the purpose of future histological, molecular and genetic analysis.

July 2004 – July 2005
Cedar Sinai Maxine Dunitz Neurosurgical Institute (Research Fellow)

July 2002 – Sept 2002
John Yu, M.D., National Medical Fellowship (Research Fellow)
“Stage directed augmentation of dendritic cell function.”
The objective of this study focused on infecting immature human dendritic cells with TRAIL loaded adenovirus as a means of enhancing induction of apoptosis in human glioblastoma multiforme cell lines.

May 2001 – Sept 2001
Genson Fujikawa, M.D., Research Assistant
“Analysis of spontaneously occurring programmed cell death in adult rats.”
The objective of this study was to analyze programmed cell death in various regions of the adult rat brain and perform a regression analysis correlation of adult rat age with the occurrence of apoptotic cells.

1999 – May 2000
USC Psychology, Honors Thesis Jan
“Prejudice attitudes and discriminatory behavior as a product of resentment.”
The major objectives were to identity and describe the relationship that exists between feelings of resentment and the exhibition of prejudice attitude and discriminatory behavior.

Sept 1997 – Jan 1998
Margaret Gatz, Ph.D., Research Assistant
Assisted in a study investigating the genetic origins of Alzheimer’s disease and psychodementia in the Alzheimer’s patient.

Research and Publications

Comparative effectiveness of treatment options for pediatric craniopharyngiomas.

Ali ZS, Bailey RL, Daniels LB, Vakhshori V, Lewis DJ, Hossain AT, Sitterley KY, Lee JY, Storm PB, Heuer GG, Stein SC.
J Neurosurg Pediatr. 2014 Feb;13(2):178-88. doi: 10.3171/2013.11.PEDS1320. Epub 2013 Dec 6.
PMID: 24313659

Craniocerebral disproportion: a topical review and proposal toward a new definition, diagnosis, and treatment protocol.

Sandler AL, Goodrich JT, Daniels LB 3rd, Biswas A, Abbott R.
Childs Nerv Syst. 2013 Nov;29(11):1997-2010. doi: 10.1007/s00381-013-2257-7. Epub 2013 Aug 24. Review.
PMID: 23974969

Successful treatment of post-shunt craniocerebral disproportion by coupling gradual external cranial vault distraction with continuous intracranial pressure monitoring.

Sandler AL, Daniels LB 3rd, Staffenberg DA, Kolatch E, Goodrich JT, Abbott R.
J Neurosurg Pediatr. 2013 Jun;11(6):653-7. doi: 10.3171/2013.2.PEDS12404. Epub 2013 Mar 29.
PMID: 23540529

Infections of the spinal subdural space in children: a series of 11 contemporary cases and review of all published reports. A multinational collaborative effort.

Sandler AL, Thompson D, Goodrich JT, van Aalst J, Kolatch E, El Khashab M, Nejat F, Cornips E, Mohindra S, Gupta R, Yassari R, Daniels LB 3rd, Biswas A, Abbott R.
Childs Nerv Syst. 2013 Jan;29(1):105-17. doi: 10.1007/s00381-012-1916-4. Epub 2012 Sep 30. Review.
PMID: 23053357

Marvelous medicine: the untold story of the Wade-Dahl-Till valve.

Sandler AL, Sturrock D, Branfield J, Abbott R, Goodrich JT, Biswas A, Daniels LB 3rd, Flamm ES.
J Neurosurg Pediatr. 2012 May;9(5):482-90. doi: 10.3171/2012.1.PEDS11244.
PMID: 22546025

Glioblastoma multiforme in two non-nuclear family members.

Daniels LB, Shaya M, Nordberg ML, Shorter CD, Fowler M, Nanda A.
J La State Med Soc. 2007 Jul-Aug;159(4):215-22.
PMID: 17987960

A review of current technology in child safety seats for infants.

Daniels WL.
J Pediatr Health Care. 2006 Nov-Dec;20(6):419-23. Review. No abstract available.
PMID: 17071376

Evaluation of Blackboard as a platform for distance education delivery.

Servonsky EJ, Daniels WL, Davis BL.
ABNF J. 2005 Nov-Dec;16(6):132-5.
PMID: 16382797

The interphotoreceptor retinoid-binding protein (IRBP) of the chicken (Gallus gallus domesticus).

Stenkamp DL, Calderwood JL, Van Niel EE, Daniels LM, Gonzalez-Fernandez F.
Mol Vis. 2005 Sep 30;11:833-45.
PMID: 16254552   Free PMC Article

Harry Matundan, Ph.D.

Basic Sciences Consultant

Cell Cultures and Cell Line Generation

Dr. Harry Matundan, Ph.D., received his doctorate in biomedical sciences conferred by the Department of Biological Chemistry in the School of Medicine, of the University of California, Irvine. Dr. Matundan’s research expertise is on novel mechanisms of drug resistance in human malignant tumors. Prior to joining the Arditi Laboratory, he worked on the role of the immune system on HSV-1 challenged immunized mice. Currently in the Arditi Lab, Matundan is studying the pathogenesis mechanisms of Kawasaki disease using a novel mouse model and the contributions of the nervous system to its pathology. Dr. Matundan currently works with New Neurons in the capacity of a basic sciences consultant, helping design and oversee our neurological-oncology research studies.

Curriculum Vitae

EDUCATION:

July 2012 Department of Biological Chemistry, School of Medicine, University of California Irvine, Irvine, CA. Fall 2005-2012. PhD, Biomedical Sciences Thesis: The role of redox sensitive NRF2 transcription factor in melanoma drug resistance July 2000 Interdepartmental Neuroscience, Life Science Division of the College of Letter and Science University of California Los Angeles, Los Angeles, CA, Fall 1996-2000 BS, Neuroscience

RESEARCH EXPERIENCE:

Jun 2014-Present Department of Pediatrics Cedar-Sinai Medical Center, Los Angeles, CA Postdoctoral Research Fellow Dr. Moshe Arditi, Director, Pediatric Infectious Diseases and Immunology Studied the immune responses to an LCCWE extract, which induces a pathological vasculitis and arteritis, in a murine model of Kawasaki disease.

  • Trained in heart perfusion, dissection of heart tissue for histological sectioning.
  • Trained in cardiac aorta and abdominal aorta histological sectioning for immunostaining.
  • To study the role of IL-1-/- mediated arteritis in aortas we created a conditional KO of IL- 1 driven by a tissue specific promoter.
  • Investigated the role of TGFb in luminal myofibroblast proliferation after LCCWE induced KD in mice.

Nov 2012-Jun 2014 Department of Immunology Cedar-Sinai Medical Center, Los Angeles, CA Postdoctoral Research Scientist Dr. Homayon Ghiasi, Director of Virology Studied the role of HSV I derived glycoproteins in the suppression of the host’s immune response.

  • Created reporter constructs and transfected into cells to determine promoter activity based on a dual-luciferase promoter assay with the use of Promega’s luminometer.
  • Familiar with several plasmid transfection technologies including, lipofectamine, Amaxa’s nucleofection, and Genlatis’ gene reporter. Studied the effects of vaccine therapy on T cell response to HSV1 latency and primary infection.
  • Utilized DNA viral plasmids as vaccines to study its efficacy on HSV1 treated transgenic animals, quantifying latency, HSV1 transcripts, and T-cell response by RNA extraction and real time PCR by Taqman probes.
  • HSV 1 infections were performed on live mice, preparations included animal husbandry, viral injections into eye, and harvesting of relevant tissues for later analysis.
  • Determined the duration of viral reactivation in HSV1-infected explanted trigeminal ganglia.
  • Quantified viral loads in the infected eye of mice using viral plaque assay.
  • Quantified serum neutralizing antibody titers using 50% plaque reduction assays.
  • Used cloning, subcloning, primer design, and prepared high purity DNA plasmids using cesium DNA preparations.
  • Quantified cell populations using a cell counter by Beckman Coulter Cell counter.
  • Studied effects of GMCSF and FLT3 injections on cell immune response by FACS analysis.

Aug 2008-2012 Department of Biological Chemistry, University of California Irvine, Irvine, CA Graduate Student Researcher Advisor: Dr. Frank L. Meyskens Jr’s, Director of UCI Chao Comprehensive Cancer Center Co-Advisor: Dr. Jeff Chan

  • Characterized expression of NRF2 in human melanocytes and melanoma lines.
  • Using molecular biology techniques, western blots and tissue culture, identified NRF2 expression in cancer lines compared to normal human melanocytes.
  • Studied the role of NRF2 in chemoresistance to conventional drug treatments of metastatic melanoma lines.
  • Used cloning, subcloning, primer design, developed a stably expressing Nrf2 shRNA to knockdown endogenous levels of this transcription factor in cancer lines.
  • Developed drug assays to quantify resistance to drug treatment using MTT assays and quantify levels of synergy in multiple drug settings.
  • Studied the role of NRF2 in oncogenic driven pathways in human melanoma.
  • Studied the role of Uridine-diphosphate glucuronsyltransferase in chemoresistance in melanoma cell lines.
  • Mentored undergraduate students

June 2006-2008 Department of Biological Chemistry, University of California Irvine, Irvine, CA. Graduate Student Researcher Advisor: Dr. Paul B. Vrana

  • Developed a novel allelic usage assay for dopamine D4 receptor (DRD4) for Peromyscus.

2004-2005 Cedars-Sinai Research Institute, Los Angeles, CA Research Associate II Dr John S. Yu’s, Vice Chair, Department of Neurosurgery

  • Research involves propagating rodent bone-marrow derived neural stem cells for use in immunotherapy in rodent brain tumor models.

2001-2004 Cedars-Sinai Davis Research Institute, Los Angeles, CA Research Associate II Dr. Rich Krueger’s Lab, Department of Neonatology

  • Research interests revolved around studying the role of proteoglycans during the neurodevelopment of a neonate and its subsequent pathology to neurodegeneration.

1997 UCLA, Department of Neurology, Los Angeles, CA Research Assistant Dr. Marie-Francoise Chesslet, Department of Neurology

  • Selected for summer research in Parkinson’s and Huntington’s diseases;

1997 CARE Quarterly Research Program, UCLA Biochemistry Department, Los Angeles, CA Research Assistant Dr. Richard Weiss

  • Paid research intern in a program that encouraged careers in science.

TEACHING ASSISTANT EXPERIENCE:

Spring 2008 Bio Sci 7 – Biostatistics

  • Led discussion sections, used excel to perform statistical analyses

Fall 2006 Bio Sci 137D -Eukaryotes and Human Genetics (upper div)

  • Led section on topics of genetic concepts and graded papers

Fall 2006 Bio Sci 9D – Diseases of the 21st Century instructed by

  • Provided learning assistance to students on biological concepts and graded tests

Spring 2005 Bio Sci 30 – Biomedical Ethics

  • Facilitated discussions on bioethical dilemmas and graded papers

PUBLICATIONS:

  1. Matundan HH, Mott KR, Allen SJ, Wechsler SL, Ghiasi H. Interrelationships of primary virus replication in the eye, level of latency and time to reactivate in the trigeminal ganglia of latently infected mice. (In preparation)
  2. Matundan HH, Mott KR, Akhtar A, Breunig J, Ghiasi H. Mutations within the pathogenic region of HSV-1 gK signal sequence alter cell surface expression and neurovirulence. Journal of Virology. 2014.
  3. Matundan HH, Mott K, Ghiasi H. Role of CD8+ T cells and myeloid DCs in protection from ocular HSV-1 challenge in immunized mice. Journal of Virology. 2014.
  4. Mott KR, Maazi H, Allen SJ, Zandian M, Matundan H, Ghiasi YN, Sharifi BG, Underhill D, Ghiasi H. Batf3 deficiency is not critical for the generation of CD8α+ dendritic cells. Immunobiology. 2014.
  5. Dellinger R, Matundan HH, Ahmed A, Duong P, Meyskens FL. Anti-cancer drugs elicit reexpression of UDP-glucuronosyltransferase in melanoma cells. PLoS One. 2012;7(10):e47696.
  6. Wiley CD, Matundan HH, Duselis AR, Isaacs AT, Vrana PB. Patterns of hybrid loss of imprinting reveal tissue- and cluster-specific regulation. PLoS One. 2008;3(10):e3572.
  7. Akasaki Y, Liu G, Matundan HH, Ng H, Yuan X, Zeng Z, Black KL, Yu JS. A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells. J Biol Chem. 2006;281(10):6165-74.
  8. Kabos P, Matundan H, Zandian M, Bertolotto C, Robinson ML, Davy BE, Yu JS, Krueger RC Jr. Neural precursors express multiple chondroitin sulfate proteoglycans, including the lectican family. Biochem Biophys Res Commun. 2004;318(4):955-63.

PRESENTATIONS:

2011 Poster presenter at the 18th Society for Free Radical Biological Medicine Poster entitled “NRF2 mediates chemoresistance in melanoma” was presented at the conference, held in Atlanta, GA. 2010 Poster presenter at the 16th International Society for Pigment Cell Conference Poster entitled “Intrinsic cellular glucronidation mediates chemoresistance in melanoma” was presented at the conference held in Vancouver, CANADA. 2009 Poster presenter at the 15th Pan American Society for Pigment Cell Conference Poster entitled “Characterization of Uridine-Diphosphate Glucuronsyltransferase expression in melanoma cell lines” was presented at the conference held in Memphis, TN. 2009 Poster presenter at the Cancer Biology Training Grant Student’s Retreat Poster entitled “Characterization of Uridine-Diphosphate Glucuronsyltransferase expression in melanoma cell lines” was presented at Rancho Mirage, CA. 2007 Special Invitee at the American Society of Mammalogists Conference Selected to represent Dr. Paul Vrana Lab in the research conference held in Albuquerque, NM. 2001 Special Invitee at the Society for Neuroscience Conference Selected to represent Dr. Rich Krueger Lab in the research conference held in San Diego, CA.

AWARDS:

2014 T32 NRSA Institutional Research Postdoctoral Training Grant in Immunology Award 2010 Pan American Society for Pigment Cell Research Conference Travel Award 2010 3rd place PanAmerican Society for Pigment Cell Research Poster Award

PROFESSIONAL MEMBERSHIPS

2009-2012 Member of Pan American Society for Pigment Cell Research  

Research and Publications

Interrelationship of Primary Virus Replication, Level of Latency, and Time to Reactivation in the Trigeminal Ganglia of Latently Infected Mice.

Matundan HH, Mott KR, Allen SJ, Wang S, Bresee CJ, Ghiasi YN, Town T, Wechsler SL, Ghiasi H. J Virol. 2016 Sep 29;90(20):9533-42. doi: 10.1128/JVI.01373-16. Print 2016 Oct 15. PMID: 27512072   Free PMC Article

CD8+ T Cells Play a Bystander Role in Mice Latently Infected with Herpes Simplex Virus 1.

Mott KR, Gate D, Matundan HH, Ghiasi YN, Town T, Ghiasi H. J Virol. 2016 Apr 29;90(10):5059-67. doi: 10.1128/JVI.00255-16. Print 2016 May 15. PMID: 26962220 Free PMC Article

Mutations within the pathogenic region of herpes simplex virus 1 gK signal sequences alter cell surface expression and neurovirulence.

Matundan HH, Mott KR, Akhtar AA, Breunig JJ, Ghiasi H. J Virol. 2015 Mar;89(5):2530-42. doi: 10.1128/JVI.03506-14. Epub 2014 Dec 10. PMID: 25505072 Free PMC Article

Role of CD8+ T cells and lymphoid dendritic cells in protection from ocular herpes simplex virus 1 challenge in immunized mice.

Matundan H, Mott KR, Ghiasi H. J Virol. 2014 Jul;88(14):8016-27. doi: 10.1128/JVI.00913-14. Epub 2014 May 7. PMID: 24807710 Free PMC Article

Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cells.

Dellinger RW, Matundan HH, Ahmed AS, Duong PH, Meyskens FL Jr. PLoS One. 2012;7(10):e47696. doi: 10.1371/journal.pone.0047696. Epub 2012 Oct 22. PMID: 23110092 Free PMC Article

Patterns of hybrid loss of imprinting reveal tissue- and cluster-specific regulation.

Wiley CD, Matundan HH, Duselis AR, Isaacs AT, Vrana PB. PLoS One. 2008;3(10):e3572. doi: 10.1371/journal.pone.0003572. Epub 2008 Oct 29. PMID: 18958286 Free PMC Article

A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells.

Akasaki Y, Liu G, Matundan HH, Ng H, Yuan X, Zeng Z, Black KL, Yu JS. J Biol Chem. 2006 Mar 10;281(10):6165-74. Epub 2005 Nov 30. PMID: 16319070 Free Article

Neural precursors express multiple chondroitin sulfate proteoglycans, including the lectican family.

Kabos P, Matundan H, Zandian M, Bertolotto C, Robinson ML, Davy BE, Yu JS, Krueger RC Jr. Biochem Biophys Res Commun. 2004 Jun 11;318(4):955-63. PMID: 15147965

Biomedical Research Institute of New Jersey

The Biomedical Research Institute of New Jersey (BRInj) is a non-profit medical research organization dedicated to experimental discovery, translational medical science, and the improvement of human health.

HOSPITAL AFFILIATIONS

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Spring Lake, NJ 07762
Tel: 973.718.3360

512 Warren Ave.
Spring Lake, NJ 07762
Tel: 973.718.3360

140 E Hanover Ave #100,
Cedar Knolls, NJ 07927
Tel: 973.718.3360

140 E Hanover Ave #100, Cedar Knolls, NJ 07927, USA
Tel: 973.718.3360

22 West 48th Street, Ste. 300,
New York, NY 10036
Tel: 973.718.3360

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New York, NY 10036
Tel: 973.718.3360

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Tel: 973.718.3360
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140 E Hanover Ave 100, Cedar Knolls, NJ 07927, USA
Tel: 973.718.3360
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22 West 48th Street, Ste. 300, New York, NY 10036
Tel: 973.718.3360

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